Gene Signature Is Associated with Early Stage Rectal Cancer Recurrence

Abstract excerpt

BACKGROUND: Despite expected excellent outcomes of surgical resection for early stage rectal cancers, 20% of stage I and II rectal cancers recur. Identifying biologic factors that predict the subset prone to recur could allow more directed therapy. This study identifies a tumor gene expression profile that accurately predicts disease recurrence. STUDY DESIGN: Stage I/II rectal cancer patients treated by surgery...

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