Article
Extended LTA, TNF, LST1 and HLA gene haplotypes and their association with rubella vaccine-induced immunity.
PloS one - 27 Jul 2010
Ovsyannikova Inna G, Vierkant Robert A, Pankratz V Shane, Jacobson Robert M, Poland Gregory A
Abstract excerpt
BACKGROUND: Recent studies have suggested the importance of HLA genes in determining immune responses following rubella vaccine. The telomeric class III region of the HLA complex harbors several genes, including lymphotoxin alpha (LTA), tumor necrosis factor (TNF) and leukocyte specific transcript -1 (LST1) genes, located between the class I B and class II DRB1 loci. Apart from HLA, little is known about the...
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