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Article

MHC class I presentation and regulation by IFN in bony fish determined by molecular analysis of the class I locus in grass carp.

Journal of immunology (Baltimore, Md. : 1950) - 15 Aug 2010

Chen Weihong, Jia Zhenghu, Zhang Ting, Zhang Nianzhi, Lin Changyou, Gao Feng, Wang Li, Li Xiaoying, Jiang Yinan, Li Xin, Gao George F, Xia Chun

Abstract excerpt

Beyond their sequences, little is known regarding MHC class I presentation and regulation by IFN in bony fish. In this work, the class I locus (Ctid-UBA) was isolated from a grass carp fosmid library, and its polymorphisms and tissue expression were investigated. The Ctid-UBA and Ctid-beta2-microglobulin genes then were expressed and refolded, and tetramer techniques were used to identify the CTL response. The...

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PMID: 20660353
DOI: 10.4049/jimmunol.1000347

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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