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Article

Toxicoepigenetic Alteration of the Kidney Injury Molecule 1 Gene in Gentamicin-Exposed Rat Kidney

21 Jul 2010

Abstract excerpt

Chromatin modifications are now widely accepted as being essential steps involved in activation, repression, and poising of the expression of a large number of genes within the genome. Not only does understanding the role of such changes provide an opportunity to elucidate mechanisms controlling gene expression but in parallel offers the ability to develop novel indicative and predictive biomarkers of disease and...

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PMID: 20660082
DOI: 10.1093/toxsci/kfq202

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