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Article

First‐trimester combined screening for trisomy 21 at 7–14 weeks' gestation

23 Jul 2010

Abstract excerpt

OBJECTIVE: To establish an algorithm for first-trimester combined screening for trisomy 21 with biochemical testing from 7 to 14 weeks' gestation and ultrasound testing at 11-13 weeks. METHODS: This was a multicenter study of 886 pregnancies with trisomy 21 and 222 475 unaffected pregnancies with measurements of free β-human chorionic gonadotropin (β-hCG) and pregnancy-associated plasma protein-A (PAPP-A) at 7-14...

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PMID: 20658511
DOI: 10.1002/uog.7755

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