Article
Decoding the stoichiometric composition and organisation of bacterial metabolosomes.
Nature communications - 24 Apr 2020
Yang Mengru, Simpson Deborah M, Wenner Nicolas, Brownridge Philip, Harman Victoria M, Hinton Jay C D, Beynon Robert J, Liu Lu-Ning
Abstract excerpt
Some enteric bacteria including Salmonella have evolved the propanediol-utilising microcompartment (Pdu MCP), a specialised proteinaceous organelle that is essential for 1,2-propanediol degradation and enteric pathogenesis. Pdu MCPs are a family of bacterial microcompartments that are self-assembled from hundreds of proteins within the bacterial cytosol. Here, we seek a comprehensive understanding of the...
Topics
- Bacterial Proteins
- Biotechnology
- Catalysis
- Cytoplasm
- Gene Expression Regulation, Bacterial
- Green Fluorescent Proteins
- Mass Spectrometry
- Metabolomics
- Mutation
- Propylene Glycol
- Protein Conformation
- Proteomics
- Salmonella enterica