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Article

The reaction mechanism of allene oxide synthase: Interplay of theoretical QM/MM calculations and experimental investigations.

Archives of biochemistry and biophysics - 1 Mar 2011

Cho Kyung-Bin, Lai Wenzhen, Hamberg Mats, Raman C S, Shaik Sason

Abstract excerpt

A combined theoretical and experimental study highlights the reaction mechanism of allene oxide synthase (AOS) and its possible link to hydroperoxide lyase (HPL) pathway. A previously published study (Lee et al., Nature 455 (2008) 363) has shown that the F137 residue is of central importance in d...

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PMID: 20654573
DOI: 10.1016/j.abb.2010.07.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20654573-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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