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Article

Evolutionary divergence in the fungal response to fluconazole revealed by soft clustering.

Genome biology - 1 Jan 2010

Kuo Dwight, Tan Kai, Zinman Guy, Ravasi Timothy, Bar-Joseph Ziv, Ideker Trey

Abstract excerpt

BACKGROUND: Fungal infections are an emerging health risk, especially those involving yeast that are resistant to antifungal agents. To understand the range of mechanisms by which yeasts can respond to anti-fungals, we compared gene expression patterns across three evolutionarily distant species - Saccharomyces cerevisiae, Candida glabrata and Kluyveromyces lactis - over time following fluconazole exposure....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20653936
DOI: 10.1186/gb-2010-11-7-r77
PMCID: PMC2926788

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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