Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Targets for cystic fibrosis therapy: proteomic analysis and correction of mutant cystic fibrosis transmembrane conductance regulator.

Expert review of proteomics - 1 Aug 2010

Collawn James F, Fu Lianwu, Bebok Zsuzsa

Abstract excerpt

Proteomic analysis has proved to be an important tool for understanding the complex nature of genetic disorders, such as cystic fibrosis (CF), by defining the cellular protein environment (proteome) associated with wild-type and mutant proteins. Proteomic screens identified the proteome of CF transmembrane conductance regulator (CFTR), and provided fundamental information to studies designed for understanding the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cystic Fibrosis
Share to Cystic Fibrosis Transmembrane Conductance Regulator

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Discovery

Share to Drug Evaluation, Preclinical

Share to CFTR gene

Share to Mutation

Share to Proteomics

Source

Open in PubMed Open full text

Identifiers

PMID: 20653506
DOI: 10.1586/epr.10.45
PMCID: PMC2927865

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Targets for cystic fibrosis therapy: proteomic analysis and correction of mutant cystic fibrosis transmembrane conductance regulator.PMID 20653506Read ↗

Transcriptomic and Proteostasis Networks of CFTR and the Development of Small Molecule Modulators for the Treatment of Cystic Fibrosis Lung Disease.Semantic proximity Read ↗

Therapeutic approaches to CFTR dysfunction: From discovery to drug development.Semantic proximity Read ↗

Molecular mechanisms of cystic fibrosis - how mutations lead to misfunction and guide therapy.Semantic proximity Read ↗

Proteomics and Metabolomics for Cystic Fibrosis Research.Semantic proximity Read ↗

CFTR Folding: From Structure and Proteostasis to Cystic Fibrosis Personalized Medicine.Semantic proximity Read ↗

Genetics of cystic fibrosis: CFTR mutation classifications toward genotype-based CF therapies.Semantic proximity Read ↗

Cystic fibrosis transmembrane conductance regulator intracellular processing, trafficking, and opportunities for mutation-specific treatment.Semantic proximity Read ↗

Functional Consequences of CFTR Interactions in Cystic Fibrosis.Semantic proximity Read ↗

Molecular targeting of CFTR as a therapeutic approach to cystic fibrosis.Semantic proximity Read ↗

Emerging drug treatments for cystic fibrosis.Semantic proximity Read ↗

Proteostasis Landscapes of Cystic Fibrosis Variants Reveals Drug Response VulnerabilitySemantic proximity Read ↗

Targeting CFTR: how to treat cystic fibrosis by CFTR-repairing therapies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.