Article
Lack of association between ADRA2B-4825 gene insertion/deletion polymorphism and migraine in Chinese Han population.
Neuroscience bulletin - 1 Aug 2010
Ni Jian-Qiang, Jia Sha-Sha, Liu Min, Chen Shou-Gong, Jiang Yu-Ting, Dong Wan-Li, Gao Yu-Zhen
Abstract excerpt
OBJECTIVE: The present study aimed to estimate the association between susceptibility to migraine and the 12-nucleotide insertion/deletion (indel) polymorphism in promoter region of alpha(2B)-adrenergic receptor gene (ADRA2B). METHODS: A case-control study was carried out in Chinese Han population, including 368 cases of migraine and 517 controls. Genomic DNA was extracted from blood samples, and DNA fragments...
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