Article
Continuous-time modeling of cell fate determination in Arabidopsis flowers.
BMC systems biology - 22 Jul 2010
van Mourik Simon, van Dijk Aalt D J, de Gee Maarten, Immink Richard G H, Kaufmann Kerstin, Angenent Gerco C, van Ham Roeland C H J, Molenaar Jaap
Abstract excerpt
BACKGROUND: The genetic control of floral organ specification is currently being investigated by various approaches, both experimentally and through modeling. Models and simulations have mostly involved boolean or related methods, and so far a quantitative, continuous-time approach has not been explored. RESULTS: We propose an ordinary differential equation (ODE) model that describes the gene expression dynamics...
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