Article
Small peptides switch the transcriptional activity of Shavenbaby during Drosophila embryogenesis.
Science (New York, N.Y.) - 16 Jul 2010
Kondo T, Plaza S, Zanet J, Benrabah E, Valenti P, Hashimoto Y, Kobayashi S, Payre F, Kageyama Y
Abstract excerpt
A substantial proportion of eukaryotic transcripts are considered to be noncoding RNAs because they contain only short open reading frames (sORFs). Recent findings suggest, however, that some sORFs encode small bioactive peptides. Here, we show that peptides of 11 to 32 amino acids encoded by the polished rice (pri) sORF gene control epidermal differentiation in Drosophila by modifying the transcription factor...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.