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Increased programmed death-ligand-1 expression in human gastric epithelial cells inHelicobacter pyloriinfection

14 Jul 2010

Abstract excerpt

B7-H1 [programmed death-ligand-1 (PD-L1)] is a B7-family member that binds to programmed death-1 (PD-1). Recently, deficiency of PD-L1 has been demonstrated to result in accelerated gastric epithelial cell damage in gastritis, and PD-L1 is suggested to play a critical role in regulating T cell homeostasis. Here, we aimed to gain more insight into gastric PD-L1 expression, regulation and function during...

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PMID: 20646001
DOI: 10.1111/j.1365-2249.2010.04217.x

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