Article
[The structure and mechanism of the action of type-IB DNA topoisomerases].
Bioorganicheskaia khimiia - 1 Jan 2000
Bugreev D V, Nevinskiĭ G A
Abstract excerpt
DNA topoisomerases responsible for the superspiralization of genomic DNA participate in almost all vitally important cell processes, including replication, transcription, and recombination, and are essential for normal cell functioning. The present review summarizes published data for type-IB topoisomerases. The results concerning the thermodynamic, structural, and kinetic aspects of the functioning of...
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