Article
A Gene-Set Enrichment and Protein-Protein Interaction Network-Based GWAS with Regulatory SNPs Identifies Candidate Genes and Pathways Associated with Carcass Traits in Hanwoo Cattle.
Genes - 16 Mar 2020
Srikanth Krishnamoorthy, Lee Seung-Hwan, Chung Ki-Yong, Park Jong-Eun, Jang Gul-Won, Park Mi-Rim, Kim Na Yeon, Kim Tae-Hun, Chai Han-Ha, Park Won Cheoul, Lim Dajeong
Abstract excerpt
Non-synonymous SNPs and protein coding SNPs within the promoter region of genes (regulatory SNPs) might have a significant effect on carcass traits. Imputed sequence level data of 10,215 Hanwoo bulls, annotated and filtered to include only regulatory SNPs (450,062 SNPs), were used in a genome-wide association study (GWAS) to identify loci associated with backfat thickness (BFT), carcass weight (CWT), eye muscle...
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