Article
The K153R variant in the myostatin gene and sarcopenia at the end of the human lifespan.
Age (Dordrecht, Netherlands) - 1 Sept 2010
González-Freire Marta, Rodríguez-Romo Gabriel, Santiago Catalina, Bustamante-Ara Natalia, Yvert Thomas, Gómez-Gallego Félix, Serra Rexach José A, Ruiz Jonatan R, Lucia Alejandro
Abstract excerpt
We studied the A55T, E164K, I225T, K153R and P198A variants in the myostatin (GDF8) gene, muscle strength and mass, and physical function during daily living in 41 nonagenarians [33 women, age range, 90, 97]. No participant carried a mutant allele of the aforementioned variants, except three part...
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