Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genes and the ageing muscle: a review on genetic association studies.

Age (Dordrecht, Netherlands) - 1 Feb 2013

Garatachea Nuria, Lucía Alejandro

Abstract excerpt

Western populations are living longer. Ageing decline in muscle mass and strength (i.e. sarcopenia) is becoming a growing public health problem, as it contributes to the decreased capacity for independent living. It is thus important to determine those genetic factors that interact with ageing and thus modulate functional capacity and skeletal muscle phenotypes in older people. It would be also clinically...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Gene Expression Regulation, Developmental
Share to Genetic Association Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Muscle Contraction

Share to Muscle Proteins

Share to Muscle, Skeletal

Share to Polymorphism, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 22037866
DOI: 10.1007/s11357-011-9327-0
PMCID: PMC3543750

Genes

ACTN3
MSTN
ACE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genes and the ageing muscle: a review on genetic association studies.PMID 22037866Read ↗

Genetic Associations with Aging Muscle: A Systematic Review.Semantic proximity Read ↗

Single and combined influence of ACE and ACTN3 genotypes on muscle phenotypes in octogenarians.Semantic proximity Read ↗

ACE and ACTN3 genotypes in older women: muscular phenotypes.Semantic proximity Read ↗

Is there a relationship between ACTN3 R577X gene polymorphism and sarcopenia?Semantic proximity Read ↗

ACTN3, Morbidity, and Healthy AgingSemantic proximity Read ↗

Strength and Endurance Training in Older Women in Relation to ACTN3 R577X and ACE I/D Polymorphisms.Semantic proximity Read ↗

Muscular Strength and Quality of Life in Older Adults: The Role of ACTN3 R577X Polymorphism.Semantic proximity Read ↗

ACE I/D and ACTN3 R/X polymorphisms and muscle function and muscularity of older Caucasian men.Semantic proximity Read ↗

Association of alpha-actinin-3 genotype with muscle mass and physical function in community-dwelling older adults.Semantic proximity Read ↗

ACE and ACTN3 genes and muscle phenotypes in nonagenarians.Semantic proximity Read ↗

ACE I/D and ACTN3 R/X polymorphisms as potential factors in modulating exercise-related phenotypes in older women in response to a muscle power training stimuli.Semantic proximity Read ↗

Are 'endurance' alleles 'survival' alleles? Insights from the ACTN3 R577X polymorphism.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.