Article
The c.469+46_56del mutation in the homeobox MSX1 gene--a novel risk factor in breast cancer?
Cancer epidemiology - 1 Oct 2010
Sliwinski Tomasz, Synowiec Ewelina, Czarny Piotr, Gomulak Paulina, Forma Ewa, Morawiec Zbigniew, Morawiec Jan, Dziki Lukasz, Wasylecka Maja, Blasiak Janusz
Abstract excerpt
PURPOSE: The aim of this study was to investigate the association of a 11 nucleotide deletion, the c.469+46_56del mutation, in the intron of the homeobox MSX1 gene and breast cancer occurrence and characteristics. METHODS: The mutation was genotyped in peripheral blood lymphocytes of 200 breast cancer patients and 203 controls by single-strand conformational PCR and DNA sequencing. RESULTS: The del/del variant of...
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