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Article

Polymorphisms in CACNA1E and Camk2d are associated with seizure susceptibility of Sprague-Dawley rats.

Epilepsy research - 1 Sept 2010

Rijkers Kim, Mescheriakova Julia, Majoie Marian, Lemmens Evi, van Wijk Xander, Philippens Marjan, Van Kranen-Mastenbroek Vivianne, Schijns Olaf, Vles Johannes, Hoogland Govert

Abstract excerpt

Seizures are associated with high intracellular calcium levels. However, conditions characterized by high intracellular calcium levels, such as stroke or traumatic brain injury, do not always evoke epilepsy. We hypothesized that polymorphisms in calcium-related genes CACNA1E and Camk2d contribute to the individual variability in seizure susceptibility. The distribution of one single nucleotide polymorphism (SNP)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20638246
DOI: 10.1016/j.eplepsyres.2010.06.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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