Article
Association of the HLA-G gene polymorphism with multiple sclerosis in a Polish population.
International journal of immunogenetics - 1 Aug 2010
Wiśniewski A, Bilińska M, Klimczak A, Wagner M, Majorczyk E, Nowak I, Pokryszko-Dragan A, Kuśnierczyk P
Abstract excerpt
Summary In this study, three polymorphic sites in the HLA-G gene: -725C>G>T, -716T>G and 14bp(indel) were genotyped. Significant differences were found between patients and controls in the alleles and genotypes for -725C>G>T and in three-point haplotypes. We observed also a significant difference in the age of disease onset between patients positive and negative for 14bp(ins). The results suggest that single...
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