Article
Therapeutic antibodies: Discovery and development using the ProteOn XPR36 biosensor interaction array system.
Analytical biochemistry - 15 Nov 2010
Bronner Vered, Denkberg Galit, Peled Mira, Elbaz Yael, Zahavi Efrat, Kasoto Harel, Reiter Yoram, Notcovich Ariel, Bravman Tsafrir
Abstract excerpt
Therapeutic monoclonal antibodies are becoming a significant and rapidly growing class of therapeutic pharmaceuticals. Their discovery and development requires fast and high-throughput methodologies for screening and selecting appropriate candidate antibodies having high affinity for the target as well as high specificity and low cross-reactivity. This study demonstrates the use of the ProteOn XPR36 protein...
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