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MicroRNA expression distinguishes SCLC from NSCLC lung tumor cells and suggests a possible pathological relationship between SCLCs and NSCLCs

17 Jun 2010

Abstract excerpt

BACKGROUND: Recent studies have shown that microRNAs (miRNAs) play roles in tumorigenesis and are reliable classifiers of certain cancer types and subtypes. However, the role of miRNAs in the pathogenesis and diagnosis of small cell carcinoma (SCLC), the majority of which represent the most aggressive lung tumors, has not been investigated. METHODS: In order to explore miRNA involvement in the pathogenesis of...

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PMID: 20624269
DOI: 10.1186/1756-9966-29-75

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