Reduced Azithromycin Susceptibility in <i>Shigella sonnei</i> , United States

Abstract excerpt

To investigate azithromycin susceptibility in Shigella sonnei in the United States, we examined the azithromycin minimum inhibitory concentrations (MICs) of outbreak and routine human S. sonnei isolates. Isolate susceptibility clustered at 8 mg/L, but three isolates displayed higher MICs (>64 mg/L) to azithromycin. All three isolates contained a plasmid-encoded mphA gene, known to encode a...

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