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Multidrug-resistant conjugative plasmid carrying mphA confers increased antimicrobial resistance in Shigella

23 Mar 2024

Abstract excerpt

Shigellosis remains a common gastrointestinal disease mostly in children < 5 years of age in developing countries. Azithromycin (AZM), a macrolide, is currently the first-line treatment for shigellosis in Bangladesh; ciprofloxacin (CIP) and ceftriaxone (CRO) are also used frequently. We aimed to evaluate the current epidemiology of antimicrobial resistance (AMR) and mechanism(s) of increasing macrolide resistance...

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PMID: 38521802
DOI: 10.1038/s41598-024-57423-1

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