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Article

MHC heterozygosity and survival in red junglefowl.

Molecular ecology - 1 Aug 2010

Worley Kirsty, Collet Julie, Spurgin Lewis G, Cornwallis Charlie, Pizzari Tommaso, Richardson David S

Abstract excerpt

Genes of the major histocompatibility complex (MHC) form a vital part of the vertebrate immune system and play a major role in pathogen resistance. The extremely high levels of polymorphism observed at the MHC are hypothesised to be driven by pathogen-mediated selection. Although the exact nature of selection remains unclear, three main hypotheses have been put forward; heterozygote advantage, negative...

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Identifiers

PMID: 20618904
DOI: 10.1111/j.1365-294X.2010.04724.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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