Article
Bistability in two-locus models with selection, mutation, and recombination.
Journal of mathematical biology - 1 May 2011
Park Su-Chan, Krug Joachim
Abstract excerpt
The evolutionary effect of recombination depends crucially on the epistatic interactions between linked loci. A paradigmatic case where recombination is known to be strongly disadvantageous is a two-locus fitness landscape displaying reciprocal sign epistasis with two fitness peaks of unequal height. Although this type of model has been studied since the 1960s, a full analytic understanding of the stationary...
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