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Article

Interaction of selection and recombination in the fixation of negative-epistatic genes.

Genetical research - 1 Jun 1996

Michalakis Y, Slatkin M

Abstract excerpt

We investigated the interaction of recombination and selection on the process of fixation of two linked loci with epistatic interactions in fitness. We consider both the probability of fixation of newly arising mutants (the static model) and the time to fixation under continued mutation (the dynamic model). Our results show that the fixation of a new advantageous combination is facilitated by higher fitness of...

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Identifiers

PMID: 8690274
DOI: 10.1017/s0016672300033747

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Source receipt: pubmed, retrieved 7 Sept 2026.

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