Article
Inherited variations in AR, ESR1, and ESR2 genes are not associated with prostate cancer aggressiveness or with efficacy of androgen deprivation therapy.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jul 2010
Sun Tong, Lee Gwo-Shu Mary, Werner Lillian, Pomerantz Mark, Oh William K, Kantoff Philip W, Freedman Matthew L
Abstract excerpt
BACKGROUND: Sex steroid hormone receptors mediate essential processes in normal prostate growth and contribute to prostate cancer development. METHOD: In this study, we investigated the association between common inherited variation of the AR, ESR1, and ESR2 genes and two clinically relevant trai...
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