Article
Acanthamoeba produces disseminated infection in locusts and traverses the locust blood-brain barrier to invade the central nervous system.
BMC microbiology - 8 Jul 2010
Mortazavi Parisa N, Goldsworthy Graham, Kirk Ruth, Khan Naveed A
Abstract excerpt
BACKGROUND: Many aspects of Acanthamoeba granulomatous encephalitis remain poorly understood, including host susceptibility and chronic colonization which represent important features of the spectrum of host-pathogen interactions. Previous studies have suggested locusts as a tractable model in which to study Acanthamoeba pathogenesis. Here we determined the mode of parasite invasion of the central nervous system...
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