Article
Novel model for the in vivo study of central nervous system infection due to Acanthamoeba spp. (T4 genotype).
Journal of medical microbiology - 1 Apr 2009
Mortazavi Parisa Nakhostin, Goldsworthy Graham, Kirk Ruth, Khan Naveed Ahmed
Abstract excerpt
In this study it was shown for what is believed to be the first time that the African migratory locust can be used as a model for the study of Acanthamoeba pathogenesis. Mature adult locusts were injected intra-abdominally with 10 mul suspension of 10(6) Acanthamoeba (a clinical isolate of the T4 genotype) in culture medium, or with the same volume of sterile culture medium. Locusts injected with Acanthamoeba...
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