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Article

Approach to the patient with resistance to thyroid hormone and pregnancy.

The Journal of clinical endocrinology and metabolism - 1 Jul 2010

Weiss Roy E, Dumitrescu Alexandra, Refetoff Samuel

Abstract excerpt

Resistance to thyroid hormone (RTH), a syndrome of reduced end-organ responsiveness to thyroid hormone (TH), is mostly caused by mutations in the TH receptor (TR) beta gene. Diagnosis is based on persistent elevations of serum free T(4) and often T(3) levels in the absence of TSH suppression, and confirmation in most cases is by way of genetic testing. The mainstay in the management of RTH patients who are...

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Source

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Identifiers

PMID: 20610605
DOI: 10.1210/jc.2010-0409
PMCID: PMC2928892

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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