Article
Is fetuin-A a mortality risk factor in dialysis patients or a mere risk marker? A Mendelian randomization approach.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Jan 2011
Verduijn Marion, Prein Robert A, Stenvinkel Peter, Carrero Juan Jesús, le Cessie Saskia, Witasp Anna, Nordfors Louise, Krediet Ray T, Boeschoten Elisabeth W, Dekker Friedo W
Abstract excerpt
BACKGROUND: Low levels of circulating fetuin-A are associated with increased mortality in dialysis patients. This study aimed to examine a potential causative role for fetuin-A on mortality by investigating whether a functional polymorphism in the alpha2-Heremans-Schmid glycoprotein (AHSG) gene associates with mortality, and by estimating the causative effect of fetuin-A levels on mortality using a Mendelian...
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