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Alpha 2-Heremans-Schmid glycoprotein gene polymorphism (rs4918) is associated with coronary artery calcification in incident peritoneal dialysis patients.

Nephrology (Carlton, Vic.) - 1 Jan 2023

Dai Shuqi, Chen Yun, Shang Da, Ge Xiaolin, Yan Huanqing, Hao Chuanming, Zhu Tongying

Abstract excerpt

AIM: Coronary artery calcification (CAC) is a common and severe complication in peritoneal dialysis (PD) patients, and it progresses in a majority of patients. Fetuin-A, encoded by the alpha 2-Heremans-Schmid glycoprotein (AHSG) gene, is a serum calcification inhibitor. The study aimed to examine the role of AHSG gene polymorphism rs4918 in CAC and CAC progression of PD patients. METHODS: Incident PD patients at...

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PMID: 36314193
DOI: 10.1111/nep.14126

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