Article
Comparative Multi-Epitope-Ligand-Cartography reveals essential immunological alterations in Barrett's metaplasia and esophageal adenocarcinoma.
Molecular cancer - 6 Jul 2010
Berndt Uta, Philipsen Lars, Bartsch Sebastian, Hu Yuqin, Röcken Christoph, Bertram Wiedenmann, Hämmerle Marcus, Rösch Thomas, Sturm Andreas
Abstract excerpt
BACKGROUND: Barrett's esophagus (BE) is caused by gastroesophageal reflux with consecutive mucosal inflammation, predisposing patients to the development of esophageal adenocarcinoma (EAC). We investigated changes in T cell-related mucosal combinatorial molecular protein patterns in both diseases using the novel Multi-Epitope-Ligand-Cartography, a unique robotic whole-cell imaging technology that simultaneously...
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