Article
In silico characterization of the functional and structural modules of the hemagglutinin protein from the swine-origin influenza virus A (H1N1)-2009.
Science China. Life sciences - 1 Jun 2010
Sun YePing, Shi Yi, Zhang Wei, Li Qing, Liu Di, Vavricka Christopher, Yan JingHua, Gao George F
Abstract excerpt
The 2009 swine-origin influenza virus (S-OIV, H1N1 subtype) has developed into a new pandemic influenza as announced by the World Health Organization. In order to uncover clues about the determinants for virulence and pathogenicity of the virus, we characterized the functional modules of the surface glycoprotein hemagglutinin (HA), the most important protein in molecular epidemiology and pathogenesis of influenza...
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