Article
Pathogenicity of highly pathogenic avian H5N1 influenza A viruses isolated from humans between 2003 and 2008 in northern Vietnam.
The Journal of general virology - 1 Oct 2010
Le Quynh Mai, Ito Mutsumi, Muramoto Yukiko, Hoang Phuong Vu Mai, Vuong Cuong Duc, Sakai-Tagawa Yuko, Kiso Maki, Ozawa Makoto, Takano Ryo, Kawaoka Yoshihiro
Abstract excerpt
Vietnam is one of the countries most affected by highly pathogenic H5N1 influenza A viruses. To evaluate the potential pathogenicity in mammals of H5N1 viruses isolated from humans in Vietnam, we determined the sequences of all eight genes of 22 human isolates collected between 2003 and 2008 and compared their virulence in mice. The isolates were classified into clade 1 and clade 2.3.4 and differed in...
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