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Article

Endoreplication controls cell fate maintenance.

PLoS genetics - 24 Jun 2010

Bramsiepe Jonathan, Wester Katja, Weinl Christina, Roodbarkelari Farshad, Kasili Remmy, Larkin John C, Hülskamp Martin, Schnittger Arp

Abstract excerpt

Cell-fate specification is typically thought to precede and determine cell-cycle regulation during differentiation. Here we show that endoreplication, also known as endoreduplication, a specialized cell-cycle variant often associated with cell differentiation but also frequently occurring in malignant cells, plays a role in maintaining cell fate. For our study we have used Arabidopsis trichomes as a model system...

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Identifiers

PMID: 20585618
DOI: 10.1371/journal.pgen.1000996
PMCID: PMC2891705

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Endoreplication controls cell fate maintenance.PMID 20585618Read ↗

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