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Article

Cullin 4-ring finger-ligase plays a key role in the control of endoreplication cycles in Arabidopsis trichomes.

Proceedings of the National Academy of Sciences of the United States of America - 24 Aug 2010

Roodbarkelari Farshad, Bramsiepe Jonathan, Weinl Christina, Marquardt Sebastian, Novák Béla, Jakoby Marc J, Lechner Esther, Genschik Pascal, Schnittger Arp

Abstract excerpt

One of the predominant cell-cycle programs found in mature tissues is endoreplication, also known as endoreduplication, that leads to cellular polyploidy. A key question for the understanding of endoreplication cycles is how oscillating levels of cyclin-dependent kinase activity are generated tha...

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Identifiers

PMID: 20696906
DOI: 10.1073/pnas.1006941107
PMCID: PMC2930562

Genes

APC
RBX1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20696906-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Cullin 4-ring finger-ligase plays a key role in the control of endoreplication cycles in Arabidopsis trichomes.PMID 20696906Read ↗

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GIGAS CELL1, a novel negative regulator of the anaphase-promoting complex/cyclosome, is required for proper mitotic progression and cell fate determination in Arabidopsis.Semantic proximity Read ↗

New insights into the control of endoreduplication: endoreduplication could be driven by organ growth in Arabidopsis leaves.Semantic proximity Read ↗

Misexpression of the cyclin-dependent kinase inhibitor ICK1/KRP1 in single-celled Arabidopsis trichomes reduces endoreduplication and cell size and induces cell death.Semantic proximity Read ↗

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