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Article

Genes of the ecdysone biosynthesis pathway are regulated by the dATAC histone acetyltransferase complex in Drosophila.

Molecular and cellular biology - 1 Sept 2010

Pankotai T, Popescu C, Martín D, Grau B, Zsindely N, Bodai L, Tora L, Ferrús A, Boros I

Abstract excerpt

Uncovering mechanisms that regulate ecdysone production is an important step toward understanding the regulation of insect metamorphosis and processes in steroid-related pathologies. We report here the transcriptome analysis of Drosophila melanogaster dAda2a and dAda3 mutants, in which subunits of the ATAC acetyltransferase complex are affected. In agreement with the fact that these mutations lead to lethality at...

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Identifiers

PMID: 20584983
DOI: 10.1128/MCB.00142-10
PMCID: PMC2937542

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Source receipt: pubmed, retrieved 7 Sept 2026.

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