Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An 8-gene qRT-PCR-based gene expression score that has prognostic value in early breast cancer.

BMC cancer - 28 Jun 2010

Sánchez-Navarro Iker, Gámez-Pozo Angelo, Pinto Alvaro, Hardisson David, Madero Rosario, López Rocío, San José Belén, Zamora Pilar, Redondo Andrés, Feliu Jaime, Cejas Paloma, González Barón Manuel, Angel Fresno Vara Juan, Espinosa Enrique

Abstract excerpt

BACKGROUND: Gene expression profiling may improve prognostic accuracy in patients with early breast cancer. Our objective was to demonstrate that it is possible to develop a simple molecular signature to predict distant relapse. METHODS: We included 153 patients with stage I-II hormonal receptor-positive breast cancer. RNA was isolated from formalin-fixed paraffin-embedded samples and qRT-PCR amplification of 83...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Databases, Genetic
Share to Kaplan-Meier Estimate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasm Staging

Share to Paraffin Embedding

Share to Predictive Value of Tests

Share to Proportional Hazards Models

Share to Reproducibility of Results

Share to Risk Assessment

Source

Open in PubMed Open full text

Identifiers

PMID: 20584321
DOI: 10.1186/1471-2407-10-336
PMCID: PMC2906483

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An 8-gene qRT-PCR-based gene expression score that has prognostic value in early breast cancer.PMID 20584321Read ↗

Validation and Clinical Utility of a 70-Gene Prognostic Signature for Women With Node-Negative Breast CancerSemantic proximity Read ↗

The 70-gene prognosis-signature predicts disease outcome in breast cancer patients with 1–3 positive lymph nodes in an independent validation studySemantic proximity Read ↗

The 70-gene prognosis signature predicts early metastasis in breast cancer patients between 55 and 70 years of ageSemantic proximity Read ↗

Systematic assessment of prognostic gene signatures for breast cancer shows distinct influence of time and ER statusSemantic proximity Read ↗

70-Gene Signature as an Aid to Treatment Decisions in Early-Stage Breast Cancer.Semantic proximity Read ↗

Identification of a low-risk subgroup of HER-2-positive breast cancer by the 70-gene prognosis signatureSemantic proximity Read ↗

Validation and Clinical Utility of a 70-Gene Prognostic Signature for Women With Node-Negative Breast CancerSemantic proximity Read ↗

Development and clinical utility of a 21-gene recurrence score prognostic assay in patients with early breast cancer treated with tamoxifen.Semantic proximity Read ↗

Clinically relevant gene signatures provide independent prognostic information in older breast cancer patientsSemantic proximity Read ↗

The predictive value of the 70-gene signature for adjuvant chemotherapy in early breast cancerSemantic proximity Read ↗

Transcriptome Analysis Derives a Novel Prognostic 7-mRNA Signature in Early-Stage Triple-Negative Breast CancerSemantic proximity Read ↗

Additional value and potential use of the 70-gene prognosis signature in node-negative breast cancer in daily clinical practice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.