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A novel microfluidic platform for size and deformability based separation and the subsequent molecular characterization of viable circulating tumor cells

20 Jan 2016

Abstract excerpt

Circulating tumor cells (CTCs) were introduced as biomarkers more than 10 years ago, but capture of viable CTCs at high purity from peripheral blood of cancer patients is still a major technical challenge. Here, we report a novel microfluidic platform designed for marker independent capture of CTCs. The Parsortix™ cell separation system provides size and deformability-based enrichment with automated staining for...

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PMID: 26789903
DOI: 10.1002/ijc.30007

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