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Article

Generation of Fgfr3 conditional knockout mice.

International journal of biological sciences - 15 Jun 2010

Su Nan, Xu Xiaoling, Li Cuiling, He Qifen, Zhao Ling, Li Can, Chen Siyu, Luo Fengtao, Yi Lingxian, Du Xiaolan, Huang Haiyang, Deng Chuxia, Chen Lin

Abstract excerpt

Fibroblast growth factor receptor 3 (FGFR3), highly conserved in both humans and murine, is one of key tyrosine kinase receptors for FGF. FGFR3 is expressed in different tissues, including cartilage, brain, kidney, and intestine at different development stages. Conventional knockout of Fgfr3 alleles leads to short life span, and overgrowth of bone. In clinic, human FGFR3 mutations are responsible for three...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptor, Fibroblast Growth Factor, Type 3

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Source

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Identifiers

PMID: 20582225
DOI: 10.7150/ijbs.6.327
PMCID: PMC2892296

Genes

FGFR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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