Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fathead minnow steroidogenesis: in silico analyses reveals tradeoffs between nominal target efficacy and robustness to cross-talk

28 Jun 2010

Abstract excerpt

BACKGROUND: Interpreting proteomic and genomic data is a major challenge in predictive ecotoxicology that can be addressed by a systems biology approach. Mathematical modeling provides an organizational platform to consolidate protein dynamics with possible genomic regulation. Here, a model of ovarian steroidogenesis in the fathead minnow, Pimephales promelas, (FHM) is developed to evaluate possible...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aquaculture disease management and microbiota
Share to Hypothalamic control of reproductive hormones
Share to Reproductive biology and impacts on aquatic species

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20579396
DOI: 10.1186/1752-0509-4-89

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fathead minnow steroidogenesis: in silico analyses reveals tradeoffs between nominal target efficacy and robustness to cross-talkPMID 20579396Read ↗

Assessing gene network stability and individual variability in the fathead minnow (Pimephales promelas) transcriptome.Semantic proximity Read ↗

Hepatic Protein Expression Networks Associated with Masculinization in the Female Fathead Minnow (<i>Pimephales promelas</i>)Semantic proximity Read ↗

Early phosphoproteomic changes for adverse outcome pathway development in the fathead minnow (Pimephales promelas) brain.Semantic proximity Read ↗

Exploring Androgen-Regulated Pathways in Teleost Fish Using Transcriptomics and ProteomicsSemantic proximity Read ↗

Model-free Identification of Phenotype-Relevant Variables From Dose Response DataSemantic proximity Read ↗

Natural Variation in Fish Transcriptomes: Comparative Analysis of the Fathead Minnow (Pimephales promelas) and Zebrafish (Danio rerio).Semantic proximity Read ↗

Transcriptomic profiling of progesterone in the male fathead minnow (Pimephales promelas) testisSemantic proximity Read ↗

Molecular circuits, biological switches, and nonlinear dose-response relationships.Semantic proximity Read ↗

Systems biology meets stress ecology: linking molecular and organismal stress responses in Daphnia magna.Semantic proximity Read ↗

Optimal Performance Objectives in the Highly Conserved Bone Morphogenetic Protein Signaling PathwaySemantic proximity Read ↗

Cloning and In Vitro Expression and Characterization of the Androgen Receptor and Isolation of Estrogen Receptor α from the Fathead Minnow (<i>Pimephales promelas</i>)Semantic proximity Read ↗

Integrating theoretical and empirical approaches for a robust understanding of endocrine flexibility.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.