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Article

Systems biology meets stress ecology: linking molecular and organismal stress responses in Daphnia magna.

Genome biology - 1 Jan 2008

Heckmann Lars-Henrik, Sibly Richard M, Connon Richard, Hooper Helen L, Hutchinson Thomas H, Maund Steve J, Hill Christopher J, Bouetard Anthony, Callaghan Amanda

Abstract excerpt

BACKGROUND: Ibuprofen and other nonsteroidal anti-inflammatory drugs have been designed to interrupt eicosanoid metabolism in mammals, but little is known of how they affect nontarget organisms. Here we report a systems biology study that simultaneously describes the transcriptomic and phenotypic stress responses of the model crustacean Daphnia magna after exposure to ibuprofen. RESULTS: Our findings reveal...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 18291039
DOI: 10.1186/gb-2008-9-2-r40
PMCID: PMC2374704

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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