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<i>Streptococcus mutans</i> Inhibits <i>Candida albicans</i> Hyphal Formation by the Fatty Acid Signaling Molecule <i>trans‐</i>2‐Decenoic Acid (SDSF)

22 Jun 2010

Abstract excerpt

In the human mouth, fungi and several hundred species of bacteria coexist. Here we report a case of interkingdom signaling in the oral cavity: A compound excreted by the caries bacterium Streptococcus mutans inhibits the morphological transition from yeast to hyphae, an important virulence trait, in the opportunistic fungus Candida albicans. The compound excreted by S. mutans was originally studied because it...

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PMID: 20572249
DOI: 10.1002/cbic.201000086

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