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First and second trimester serum tests with and without first trimester ultrasound tests for Down's syndrome screening

15 Mar 2017

Abstract excerpt

BACKGROUND: Down's syndrome occurs when a person has three copies of chromosome 21 (or the specific area of chromosome 21 implicated in causing Down's syndrome) rather than two. It is the commonest congenital cause of mental disability. Non-invasive screening based on biochemical analysis of maternal serum or urine, or fetal ultrasound measurements, allows estimates of the risk of a pregnancy being affected and...

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Share to Down syndrome and intellectual disability research
Share to Fetal and Pediatric Neurological Disorders
Share to Prenatal Screening and Diagnostics

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Identifiers

PMID: 28295159
DOI: 10.1002/14651858.cd012599

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