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Article

Predicting malignant potential of gastrointestinal stromal tumors: Role of p16 and E2F1 expression.

Applied immunohistochemistry & molecular morphology : AIMM - 1 Jul 2010

Tetikkurt Umit Seza, Ozaydin Ipek Yildiz, Ceylan Sule, Gurbuz Yesim, Erdogan Nusret, Oz Feriha

Abstract excerpt

Altered expression of cell cycle regulatory proteins in GISTs (gastrointestinal stromal tumors) may be the mechanism for their diversity in clinical behavior. The use of these tumorigenetic and cell proliferative proteins may provide an alternative route for follow-up and treatment. The aim of this study was to determine the prognostic relevance of the E2F1 and p16 expression in GISTs. Tissues from 21 cases with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cyclin-Dependent Kinase Inhibitor p16

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Share to Gene Expression Regulation, Neoplastic

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Share to Neoplasms, Second Primary

Source

Identifiers

PMID: 20571341
DOI: 10.1097/PAI.0b013e3181d245c0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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