Article
Fetally derived CCL3 is not essential for the migration of maternal cells across the blood-placental barrier in the mouse.
The Journal of veterinary medical science - 1 Nov 2010
Unno Akihiro, Suzuki Kazuhiko, Kitoh Katsuya, Takashima Yasuhiro
Abstract excerpt
In mammals with a hemochorial placenta (e.g., primates and rodents), the maternal and fetal bloodstreams are separated by the blood-placenta barrier. However, a few maternal cells in the general circulation pass through the barrier during normal pregnancy. So far, the transfer mechanism has not been investigated. In this study, we established a chemokine (C-C motif) ligand 3 (CCL3)-deficient mouse model to...
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