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Article

Biphenotypic hematologic malignancy: a case report of the 8p11 myeloproliferative syndrome in a child.

Journal of pediatric hematology/oncology - 1 Aug 2010

Chen Xiangli, Zhang Yin, Li Yulong, Lei Pingchong, Zhai Yaping, Liu Linxiang

Abstract excerpt

SUMMARY: The 8p11 myeloproliferative syndrome, also known as stem cell leukemia/lymphoma, is a rare, atypical, myeloproliferative disorder and lymphoid malignancy associated with chromosomal abnormalities involving the 8p11 chromosomal band. Translocations associated with this syndrome result in the fusion of the fibroblast growth factor receptor 1 (FGFR 1) gene with various partners, resulting in...

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Source

Identifiers

PMID: 20562652
DOI: 10.1097/MPH.0b013e3181e413fa

Genes

FGFR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Biphenotypic hematologic malignancy: a case report of the 8p11 myeloproliferative syndrome in a child.PMID 20562652Read ↗

Distinct stem cell myeloproliferative/T lymphoma syndromes induced by ZNF198-FGFR1 and BCR-FGFR1 fusion genes from 8p11 translocationsSemantic proximity Read ↗

The 8p11 myeloproliferative syndrome: Genotypic and phenotypic classification and targeted therapySemantic proximity Read ↗

The 8p11 Myeloproliferative Syndrome: A Distinct Clinical Entity Caused by Constitutive Activation of <i>FGFR1</i>Semantic proximity Read ↗

Myeloproliferative neoplasms with t(8;22)(p11.2;q11.2)/BCR-FGFR1: a meta-analysis of 20 cases shows cytogenetic progression with B-lymphoid blast phase.Semantic proximity Read ↗

[Characteristic of 8p11 Myeloproliferative Syndrome with Rare Phenotype].Semantic proximity Read ↗

LRRFIP1, a new FGFR1 partner gene associated with 8p11 myeloproliferative syndromeSemantic proximity Read ↗

Myeloid/lymphoid neoplasms with FGFR1 rearrangement.Semantic proximity Read ↗

Fusion of the <i>BCR</i> and the fibroblast growth factor receptor‐1 (<i>FGFR1</i>) genes as a result of t(8;22)(p11;q11) in a myeloproliferative disorder: The first fusion gene involving <i>BCR</i> but not <i>ABL</i>Semantic proximity Read ↗

Chromosome 8p11.2 translocations: prevalence, FISH analysis for FGFR1 and MYST3, and clinicopathologic correlates in a consecutive cohort of 13 cases from a single institution.Semantic proximity Read ↗

Identification of a novel partner gene, <i>TPR</i>, fused to <i>FGFR1</i> in 8p11 myeloproliferative syndromeSemantic proximity Read ↗

8p11 myeloproliferative syndrome: a reviewSemantic proximity Read ↗

Consistent Fusion of ZNF198 to the Fibroblast Growth Factor Receptor-1 in the t(8;13)(p11;q12) Myeloproliferative SyndromeSemantic proximity Read ↗

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