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Article

Clinical and genetic findings in a series of Italian children with pure hereditary spastic paraplegia.

European journal of neurology - 1 Jan 2011

Battini R, Fogli A, Borghetti D, Michelucci A, Perazza S, Baldinotti F, Conidi M E, Ferreri M I, Simi P, Cioni G

Abstract excerpt

BACKGROUND: hereditary spastic paraplegias (HSP) are a group of neurodegenerative disorders characterized by progressive lower extremity spastic weakness. SPG7, SPG4 and SPG3A are some of the autosomal genes recently found as mutated in recessive or dominant forms of HSP in childhood. SPG31 is mo...

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Source

Identifiers

PMID: 20550563
DOI: 10.1111/j.1468-1331.2010.03102.x

Genes

SPG7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20550563-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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